Selected Publications

Goebel, E. J., Ongaro, L., Kappes, E. C., Vestal, K., Belcheva, E., Castonguay, R., Kumar, R., Bernard, D. J. & Thompson, T. B. The orphan ligand, activin C, signals through activin receptor-like kinase 7. eLife 11, e78197 (2022).

Goebel, E. J., Kattamuri, C., Gipson, G. R., Krishnan, L., Chavez, M., Czepnik, M., Maguire, M. C., Grenha, R., Håkansson, M., Logan, D. T., Grinberg, A. V., Sako, D., Castonguay, R., Kumar, R. & Thompson, T. B. Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors. iScience 25, 103590 (2022). PDB: 7MRZ

Hart, K. N., Stocker, W. A., Nagykery, N. G., Walton, K. L., Harrison, C. A., Donahoe, P. K., Pépin, D. & Thompson, T. B. Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family. PNAS 118, (2021). PDB: 7L0J

Goebel, E. J., Corpina, R. A., Hinck, C. S., Czepnik, M., Castonguay, R., Grenha, R., Boisvert, A., Miklossy, G., Fullerton, P. T., Matzuk, M. M., Idone, V. J., Economides, A. N., Kumar, R., Hinck, A. P. & Thompson, T. B. Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity. Proc. Natl. Acad. Sci. U.S.A. 116, 15505–15513 (2019). PDB: 6MAC

Walker, R. G., McCoy, J. C., Czepnik, M., Mills, M. J., Hagg, A., Walton, K. L., Cotton, T. R., Hyvönen, M., Lee, R. T., Gregorevic, P., Harrison, C. A. & Thompson, T. B. Molecular characterization of latent GDF8 reveals mechanisms of activation. Proc. Natl. Acad. Sci. U.S.A. 115, E866–E875 (2018).